By Anthony Seaton, A. Gordon Leitch, Douglas Seaton

Now in its 5th variation, Crofton and Douglas's breathing ailments has firmly tested itself because the best medical textbook on illnesses of the chest.

Presented, for the 1st time, as a two-volume set, this vintage textual content has been thoroughly rewritten and tremendously multiplied. large revisions make sure that those volumes current an up to date assessment of all features of lung disease

. The contributions of a few 18 major gurus make sure that every one quarter is comprehensively coated and new to this variation are chapters at the genetics of lung illness, smoking, pollution, sleep apnoea, diving, lung transplantation and medico-legal facets. The alterations in content material mirror the speed of swap within the components involved not just when it comes to figuring out of the illness procedures but additionally their therapy. the one bankruptcy on bronchial asthma that seemed in prior variants, has now been elevated into 3 chapters overlaying epidemiology, mechanisms and administration, reflecting the large learn attempt at present underway following a marked bring up within the occurrence of this disorder in fresh years.

This new version keeps to supply a good reference either for the trainee and expert in breathing medication, in addition to the final health practitioner. will probably be tremendous precious at the ward and within the place of work, the place scientific difficulties come up and questions are requested which want transparent solutions.

Show description

Read Online or Download Crofton and Douglas's Respiratory Diseases PDF

Similar pulmonary & thoracic medicine books

Integrated Cardiothoracic Imaging with MDCT

The advance of speedy scanning recommendations and ultrahigh temporal solution, that are hired for either ECG-gated and nongated examinations of the chest, has made built-in cardiothoracic imaging a truth. This well timed, well-illustrated e-book, written by means of famous specialists within the box, addresses the varied parts of this topic.

Acute Exacerbations in COPD

The stated variability within the prevalence and severity of persistent breathing ailments corresponding to bronchial asthma and COPD, makes potent remedy tougher, and the social and fiscal charges of those ailments the entire higher. Acute exacerbations are multi-factorial in foundation, and are identified to be associated with a few elements together with allergens, atmospheric toxins and infectious brokers.

High Altitude Medicine and Physiology 5E

A finished replace to this preeminent and obtainable textual content, this 5th version of a bestseller used to be built as a reaction to man's makes an attempt to climb unaided to raised altitudes and to spend extra time in those stipulations for either paintings and activity. It describes the ever-expanding demanding situations that medical professionals face in facing the alterations in human body structure and specific health conditions that come up from publicity to altitude and chilly.

Sleep Medicine in Neurology

A brand new addition to the Neurology in perform sequence, Sleep medication in Neurology is a realistic consultant for neurologists diagnosing and handling sleep problems of their sufferers. As part of the sequence, quite a few function bins are highlighted all through. "Tips and tips" supply feedback on tips to increase results via functional process or sufferer wondering.

Extra resources for Crofton and Douglas's Respiratory Diseases

Example text

Vasoactive intestinal peptide is a 28-amino-acid peptide that relaxes bronchial and vascular smooth muscle and has an anti-inflammatory effect [122,128]. It has been found in human bronchial muscle, mucous glands, pulmonary and bronchial vessels, and in neutrophils, eosinophils and monocytes. It probably acts within the cell by activation of adenylate cyclase, like sympathetic stimulation, increasing levels of cyclic AMP [129]. The opposite effect, resulting in smooth muscle constriction, vasodilatation, increased vascular permeability and fluid transudation, and increased mucus secretion, is mediated via sensory nerves that respond to irritant stimuli by release of substance P, neurokinin A and calcitonin gene-related peptide [130–132].

Douglas AN. Quantitative study of bronchial mucous gland enlargement. Thorax 1980; 35: 198. Busse WW, Calhoun WF, Sedgwick JD. Mechanism of airway inflammation in asthma. Am Rev Respir Dis 1993; 147: S20. Chanez P, Lacoste JY, Guillot B et al. Mast cells’ contribution to the fibrosing alveolitis of the scleroderma lung. Am Rev Respir Dis 1993; 147: 1497. Lopez-Vidriero MT, Das I, Reid LM. Airway secretion: source, biochemical and rheological properties. In: Brain D, Proctor DF, Reid LM, eds. Respiratory Defense Mechanisms Part I.

At low alveolar pressures of CO only a small proportion of haemoglobin is saturated with CO during passage through the pulmonary capillaries, so that the PCO in the blood is small relative to the PCO in the alveoli. The relatively large difference between PACO and PcCO makes the CO method for measuring diffusion capacity more accurate and reproducible than the O2 method. In essence the techniques employed require measurement of the . 10. Simultaneous measurement of alveolar volume by He dilution also allows determination of the transfer coefficient (DLCO/VA, or KCO), which may be a more appropriate indicator of the effectiveness of gas exchange when lung volume has been lost because of either disease or surgery.

Download PDF sample

Download Crofton and Douglas's Respiratory Diseases by Anthony Seaton, A. Gordon Leitch, Douglas Seaton PDF
Rated 4.80 of 5 – based on 17 votes