By Lisa Yount
This booklet profiles the lifestyles and occupation of Craig Venter, who in 1998 introduced that his deepest corporation might map the whole human genetic series.
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Additional info for Craig Venter: Dissecting the Genome
In 1970, researchers had found that certain viruses, called retroviruses (backward viruses), contain an enzyme known as reverse transcriptase. Reverse transcriptase can make a DNA strand that matches a strand of RNA. Unlike most other organisms, retroviruses carry their genetic information in RNA rather than DNA. When they infect cells, they use reverse transcriptase to copy their RNA into a DNA form, which they insert into the DNA of the infected cells. The cells then reproduce this DNA copy of the virus’s RNA every time they reproduce their own DNA, paving the way for the making of new virus particles.
Each kind of amino acid is represented by a set of three bases in a particular order. ) A gene is a segment of a DNA molecule that contains the instructions for making one protein or carrying out one other action, such as activating another gene. In their search for the adrenalin receptor protein and its gene, Venter’s team of scientists first tried to separate the receptor from other substances in the cell membrane and purify it. After struggling with this task for two years, they learned that another laboratory had succeeded in both isolating the receptor and identifying its gene.
Craig Venter wished that there were a faster, easier way to sequence genes. (opposite page) British scientist Frederick Sanger invented the first method to be widely used for determining the base sequence in a strand of DNA. He began by separating the two intertwined strands of a DNA molecule, leaving only a single strand. He made many copies of the strand and divided them into four test tubes. To each tube he added radioactively labeled molecules that were similar, but not identical, to one of the four bases in DNA.
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